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A: It is a technique of fixing the tissue in formalin, followed by embedding them in paraffin blocks. Hence, the name is formalin-fixed paraffin-embedded (FFPE) ...

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... (HR) in cells without DSBs. This observation was the driving motivation for ... Alt-R HDR Donor Blocks are ideal for making large insertions or genomic changes.

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In contrast, phosphorylation of N-terminal cluster at serine 56 and 57 impacts kinase activity and blocks both C-NHEJ and HR. Phosphorylation of threonine 946 ...

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